Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428115 | 0.90 | MAPK1 (0.54) | CYP2C9ALDH1A1LMNATSHRPOLB | |
| SCHEMBL6948645 | 0.85 | KMT2A (0.54) | ALDH1A1LMNATSHRPOLBATM | |
| SCHEMBL8428070 | 0.84 | CA1 (0.54) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL8428126 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL8423248 | 0.82 | APP (0.43) | ALDH1A1LMNATSHR | |
| SCHEMBL8427533 | 0.80 | MAPT (0.65) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL8425552 | 0.79 | POLB (0.55) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL6948663 | 0.73 | POLB (0.52) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL9025227 | 0.72 | ALDH1A1 (0.46) | CYP2C9ALDH1A1LMNA | |
| SCHEMBL8425824 | 0.71 | KMT2A (0.49) | ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |