SCHEMBL8428202

SCHEMBL8428202

CCOC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CF

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
PKM P14618 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16640889 0.92 ALDH1A1 (0.36) PKMALDH1A1KDM4EMEN1KMT2A
SCHEMBL8165793 0.88 ALDH1A1 (0.42) PKMALDH1A1CA1CA2KDM4E
SCHEMBL8166839 0.88 ALDH1A1 (0.42) PKMALDH1A1CA1CA2KDM4E
SCHEMBL27186828 0.86 ALDH1A1 (0.43) PKMALDH1A1KDM4EMEN1KMT2A
SCHEMBL28914197 0.84 ALDH1A1 (0.39) PKMALDH1A1KDM4EMEN1KMT2A
SCHEMBL3861059 0.82 THRB (0.46) TSHRPKMALDH1A1CA1CA2
SCHEMBL2691616 0.82 THRB (0.46) TSHRPKMALDH1A1CA1CA2
SCHEMBL197278 0.82 THRB (0.46) TSHRPKMALDH1A1CA1CA2
SCHEMBL5704769 0.82 THRB (0.46) TSHRPKMALDH1A1CA1CA2
SCHEMBL5704701 0.82 THRB (0.46) TSHRPKMALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11302242-A None JP disclosed
JP-H11302242-A FLUORINE-CONTAINING QUATERNARY AMMONIUM SALT NEOS CO LTD 1999-11-02 JP disclosed