SCHEMBL842865

SCHEMBL842865

CC(C)(C)[N][SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
TAAR1 Q96RJ0 2/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL154332 0.69 ALDH1A1 (0.35) LMNAALDH1A1
SCHEMBL18398 0.65 MAPK1 (0.36) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL3691011 0.65 MAPK1 (0.36) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL8381893 0.65 ALDH1A1 (0.37) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL9499497 0.63 MAPK1 (0.35) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL153206 0.63 ALDH1A1 (0.43) LMNAMAPK1ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL1295227 0.63 MAPK1 (0.35) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL30367101 0.63 MAPK1 (0.35) LMNACYP2D6MAPK1TAAR1ALDH1A1
SCHEMBL1494198 0.63 ALDH1A1 (0.37) LMNAMAPK1TAAR1ALDH1A1ALOX15
SCHEMBL28285853 0.62 ALDH1A1 (0.38) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378340-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-19 US disclosed
US-20120238765-A1 AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-20 US disclosed
US-8222426-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-17 US disclosed
US-8142908-B2 Polymer light-emitting material comprising a conjugated polymer and compound exhibiting light emission from the triplet excited state and polymer light-emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-27 US disclosed
US-7842941-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-30 US disclosed
US-20100256396-A1 AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-07 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256396-A1 AROMATIC COMPOUND AHR, AR, NR0B1 LMNA 3205/4885CYP2D6 99/4885MAPK1 3276/4885
US-20070063190-A1 Aromatic compound AHR, AR, NR0B1 LMNA 3224/4885CYP2D6 94/4885MAPK1 3365/4885
US-20120238765-A1 AROMATIC COMPOUND AHR, AR, NR0B1 LMNA 3205/4885CYP2D6 99/4885MAPK1 3276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.