Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.53 |
| ▸ | TOP2A | P11388 | 4/20 | 0.52 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428654 | 1.00 | TK1 (0.53) | TK1TOP2ARNASE1 | |
| SCHEMBL8906732 | 0.92 | TK1 (0.57) | TK1TOP2ARNASE1 | |
| SCHEMBL8906737 | 0.92 | TK1 (0.57) | TK1TOP2ARNASE1 | |
| SCHEMBL8424862 | 0.90 | RNASE1 (0.53) | TK1TOP2ARNASE1 | |
| SCHEMBL8905683 | 0.90 | TOP2A (0.52) | TK1TOP2ARNASE1 | |
| SCHEMBL8905686 | 0.90 | TOP2A (0.52) | TK1TOP2ARNASE1 | |
| SCHEMBL8424863 | 0.90 | RNASE1 (0.53) | TK1TOP2ARNASE1 | |
| SCHEMBL14788961 | 0.89 | TOP2A (0.54) | TK1TOP2ARNASE1 | |
| SCHEMBL10079072 | 0.89 | TOP2A (0.54) | TK1TOP2ARNASE1 | |
| SCHEMBL889593 | 0.89 | TOP2A (0.54) | TK1TOP2ARNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892024-A | Bifunctional nucleosides, oligomers thereof, and methods of making and using the same | SANOFI (FR) | 1999-04-06 | — | — | US | disclosed |
| EP-0701564-A1 | BIFUNCTIONAL NUCLEOSIDES, OLIGOMERS THEREOF, AND METHODS OF MAKING AND USING THE SAME | SANOFI (FR) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994022888-A1 | BIFUNCTIONAL NUCLEOSIDES, OLIGOMERS THEREOF, AND METHODS OF MAKING AND USING THE SAME | STERLINGWINTHROP INC. (US) | 1994-10-13 | — | — | WO | disclosed |