Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428645 | 0.81 | ALOX5 (0.41) | MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL8428935 | 0.80 | SMPD1 (0.38) | THRATHRBESR1AKR1C4AKR1C3 | |
| SCHEMBL8424888 | 0.77 | SMPD1 (0.52) | ESR1PTPN11SMPD1MAPTKMT2A | |
| SCHEMBL9417145 | 0.76 | PTPN11 (0.48) | ESR1PTPN11SMPD1 | |
| SCHEMBL25795006 | 0.71 | NR5A1 (0.55) | THRATHRBESR1AKR1C4AKR1C3 | |
| SCHEMBL10574605 | 0.70 | PDE5A (0.58) | PTPN11TLR8MEN1NR1I2LMNA | |
| SCHEMBL25797784 | 0.70 | NR5A1 (0.58) | LMNACYP3A4MAPT | |
| SCHEMBL9483389 | 0.69 | THRA (0.53) | THRATHRBPTPN11CHUKDAPK3 | |
| SCHEMBL9484258 | 0.69 | THRA (0.53) | THRATHRBPTPN11CHUKDAPK3 | |
| SCHEMBL9484995 | 0.69 | THRA (0.53) | THRATHRBPTPN11CHUKDAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |