Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428688 | 0.80 | THRA (0.43) | SMPD1THRATHRBESR1AKR1C4 | |
| SCHEMBL8568175 | 0.77 | SMPD1 (0.34) | SMPD1THRATHRBPDE5APDE4A | |
| SCHEMBL8568691 | 0.75 | PDE5A (0.32) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10574605 | 0.75 | PDE5A (0.58) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7463536 | 0.70 | NR5A1 (0.42) | SMPD1THRATHRBESR1MEN1 | |
| SCHEMBL9417145 | 0.69 | PTPN11 (0.48) | SMPD1ESR1PTPN11 | |
| SCHEMBL8416989 | 0.69 | HTT (0.51) | THRBPDE5APDE4APDE4BPDE4C | |
| SCHEMBL2092371 | 0.68 | NR5A1 (0.56) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL9502198 | 0.68 | CYP1A2 (0.49) | THRATHRBPDE5APDE4APDE4B | |
| SCHEMBL8424888 | 0.68 | SMPD1 (0.52) | SMPD1KDM4EKDM4AKDM4CESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |