Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.59 |
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | RARG | P13631 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | GOT1 | P17174 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997645 | 0.85 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8873156 | 0.85 | RARA (0.57) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9453207 | 0.83 | NR1H4 (0.64) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6570369 | 0.82 | S1PR1 (0.71) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL565789 | 0.81 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL1082340 | 0.81 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL4936267 | 0.81 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8874310 | 0.81 | RARA (0.62) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8691699 | 0.81 | RARA (0.48) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8424465 | 0.81 | RARA (0.59) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776885-B1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CIRD GALDERMA (FR) | 1999-10-27 | — | — | EP | claimed |