Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.64 |
| ▸ | RARB | P10826 | 6/20 | 0.64 |
| ▸ | RARG | P13631 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | GOT1 | P17174 | 1/20 | 0.64 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570369 | 0.86 | S1PR1 (0.71) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL565789 | 0.86 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL1082340 | 0.86 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8424465 | 0.85 | RARA (0.59) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8428693 | 0.85 | RARA (0.59) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124255 | 0.85 | RARA (0.76) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8428663 | 0.85 | RARA (0.58) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8872840 | 0.84 | RARA (0.62) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8426342 | 0.84 | RARA (0.60) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL27706727 | 0.84 | RARB (0.74) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092136-A | — | — | None | — | — | JP | disclosed |
| JP-H0892136-A | NEW ADAMANTYL-SUBSTITUTED ACETYLENE COMPOUND HAVING TWO AROMATIC RINGS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THE COMPOUND, AND USES OF THE COMPOSITIONS | CIRD GALDERMA | 1996-04-09 | — | — | JP | disclosed |