Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775131 | 0.85 | PPARG (0.71) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775293 | 0.84 | MAPK1 (0.82) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775210 | 0.81 | PPARG (0.69) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL8428762 | 0.76 | MAPT (0.63) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775919 | 0.75 | KDM4E (0.64) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL3240026 | 0.75 | MAPT (0.58) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775174 | 0.74 | PPARG (0.51) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL8428563 | 0.73 | BCHE (0.65) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL9423724 | 0.73 | NOX1 (0.59) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL8426652 | 0.71 | BCHE (0.67) | PPARGKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |