SCHEMBL84289

SCHEMBL84289

CSc1ccc2c(c1)C(=O)OC2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.47
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MCL1 Q07820 1/20 0.36
GLA P06280 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TYMS P04818 1/20 0.34
MAP2K7 O14733 1/20 0.34
CDC25A P30304 1/20 0.34
CDC25B P30305 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6908020 0.83 ALOX15 (0.50) PTGS2ALOX15TDP1ALDH1A1HPGD
SCHEMBL29383846 0.83 MAOA (0.53) PTGS2ALOX15TDP1ALDH1A1MAOA
SCHEMBL301318 0.83 MAOA (0.53) PTGS2ALOX15TDP1ALDH1A1MAOA
SCHEMBL92584 0.81 MAOA (0.56) ALOX15TDP1ALDH1A1MAPTMAOA
SCHEMBL13298544 0.81 MAOA (0.56) ALOX15TDP1ALDH1A1MAPTMAOA
SCHEMBL19034747 0.78 MAOA (0.53) ALOX15TDP1ALDH1A1MAOAMAOB
SCHEMBL84478 0.78 MAOA (0.53) ALOX15TDP1ALDH1A1MAOAMAOB
SCHEMBL84479 0.76 MAOA (0.66) PTGS2ALOX15TDP1ALDH1A1KDM4E
SCHEMBL29036115 0.76 MCL1 (0.46) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL11725001 0.75 MAOA (0.59) PTGS2TDP1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162693-A1 SELF-HEALING INFRARED TRANSMITTING POLYIMIDE OPTICAL POLYMER MATERIAL HAVING HIGH REFRACTIVE INDEX, AND COMPOSITE THEREOF 연세대학교 산학협력단 2020-08-13 WO disclosed
CN-111500021-A Preparation method of flame-retardant epoxy resin composite material 山东金宝电子股份有限公司 2020-08-07 CN disclosed
US-8129496-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-06 US disclosed
US-20080219135-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING GLOBALFOUNDRIES U.S. INC. 2008-09-11 US disclosed
EP-0135153-B1 PROCESS FOR PRODUCING SUBSTITUTED PHTHALIC ACID COMPOUNDS NIPPON ZEON CO., LTD. (JP) 1988-08-10 EP disclosed
US-4684737-A Process for producing substituted phthalic acid compounds NIPPON ZEON CO., LTD. (JP) 1987-08-04 US disclosed
EP-0135153-A2 Process for producing substituted phthalic acid compounds NIPPON ZEON CO., LTD. (JP) 1985-03-27 EP disclosed
US-4025505-A ANTICONVULSANTS CIBA-GEIGY CORPORATION (US) 1977-05-24 US disclosed