Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426345 | 0.88 | PNMT (0.42) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL14069697 | 0.79 | DRD2 (0.56) | ADRA2AADRA2BADRA2CMLNRADRB2 | |
| SCHEMBL8425198 | 0.78 | MLNR (0.40) | ADRA2AADRA2BADRA2CMLNRADRB2 | |
| SCHEMBL6490826 | 0.73 | MEN1 (0.41) | PNMTADRA2AALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL8428904 | 0.73 | GRIN2B (0.38) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8035992 | 0.73 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL16650443 | 0.73 | PNMT (0.46) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL8426665 | 0.71 | PNMT (0.41) | PNMTADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL4672232 | 0.70 | SIRT2 (0.44) | PNMTADRA2AALDH1A1SMN1; SMN2GRIN2B | |
| SCHEMBL4673771 | 0.70 | GRIN2B (0.41) | PNMTADRA2AGRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925662-A | OXIDASE INHIBITORS | SYNTHELABO (FR) | 1999-07-20 | — | — | US | disclosed |