Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430774 | 0.85 | MEN1 (0.47) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL10479729 | 0.82 | LMNA (0.46) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL2716199 | 0.79 | MEN1 (0.49) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL22593912 | 0.76 | TSHR (0.48) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL182481 | 0.75 | MEN1 (0.49) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL182893 | 0.75 | FABP4 (0.49) | MEN1KMT2ASLC2A1LMNATSHR | |
| SCHEMBL2715130 | 0.74 | MEN1 (0.45) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL300478 | 0.74 | FABP4 (0.50) | MEN1KMT2ASLC2A1TSHRFABP4 | |
| SCHEMBL10216949 | 0.74 | MEN1 (0.48) | MEN1KMT2ASLC2A1HTR7HTR1A | |
| SCHEMBL14027598 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2ASLC2A1HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |