Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431085 | 0.94 | POLB (0.45) | XDHMAOBMAOAMEN1ALDH1A1 | |
| SCHEMBL8308746 | 0.88 | PLG (0.52) | XDHEGFRRETKDRMAOB | |
| SCHEMBL8309077 | 0.88 | PLG (0.52) | XDHEGFRRETKDRMAOB | |
| SCHEMBL8306319 | 0.88 | PLG (0.52) | XDHEGFRRETKDRMAOB | |
| SCHEMBL8431111 | 0.88 | CYP1B1 (0.57) | XDHEGFRRETKDRMAOB | |
| SCHEMBL8570735 | 0.87 | XDH (0.58) | XDHEGFRRETKDRCYP1B1 | |
| SCHEMBL8309778 | 0.82 | POLH (0.50) | XDHMAOBMAOACYP1B1CYP1A1 | |
| SCHEMBL8306291 | 0.81 | CYP1B1 (0.68) | XDHMAOBMAOACYP1B1MEN1 | |
| SCHEMBL8309435 | 0.80 | PLG (0.48) | EGFRRETKDRMAOBMAOA | |
| SCHEMBL4574696 | 0.80 | CYP1B1 (0.64) | XDHMAOBMAOACYP1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |