SCHEMBL8429974

SCHEMBL8429974

C=C(C)C(=O)[N]S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.49
PRSS1 P07477 2/20 0.49
PRSS2 P07478 2/20 0.49
PRSS3 P35030 2/20 0.49
HTT P42858 1/20 0.46
ALDH1A1 P00352 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.42
LMNA P02545 3/20 0.42
GAA P10253 2/20 0.42
CYP2C19 P33261 1/20 0.42
PKM P14618 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8431538 0.84 KDM4E (0.44) HTTALDH1A1KMT2ASMN1; SMN2LMNA
SCHEMBL22699663 0.71 F2 (0.68) F2PRSS1PRSS2PRSS3HTT
SCHEMBL22634995 0.70 F2 (0.61) F2PRSS1PRSS2PRSS3HTT
SCHEMBL22634996 0.70 F2 (0.61) F2PRSS1PRSS2PRSS3HTT
SCHEMBL6891327 0.70 F2 (0.61) F2PRSS1PRSS2PRSS3HTT
Methacrylic Acid SCHEMBL5083136 0.70 LMNA (0.46) HTTALDH1A1CYP1A2CYP2C9KMT2A
SCHEMBL9858159 0.70 KMT2A (0.49) F2PRSS1PRSS2PRSS3HTT
SCHEMBL10073006 0.70 F2 (0.55) F2PRSS1PRSS2PRSS3HTT
SCHEMBL5138891 0.69 F2 (0.59) F2PRSS1PRSS2PRSS3HTT
Methacrylic Acid SCHEMBL9252465 0.69 LMNA (0.45) HTTALDH1A1CYP1A2CYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730978-B1 Image-receiving sheet material, method for forming transfer image and laminate FUJI PHOTO FILM CO LTD (JP) 1999-11-17 EP disclosed
US-5576140-A MODIFIED POLYVINYL ACETAL FUJI PHOTO FILM CO., LTD. (JP) 1996-11-19 US disclosed
EP-0730978-A2 Image-receiving sheet material, method for forming transfer image and laminate FUJI PHOTO FILM CO., LTD. (JP) 1996-09-11 EP disclosed