Valine

Valine

SCHEMBL8429982

CC(C)[C@H](N)C(=O)O.CCCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.49
KIF11 P52732 1/20 0.43
SLC7A5 Q01650 1/20 0.43
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA1 P00915 3/20 0.39
GAA P10253 1/20 0.39
CASR P41180 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL21352576 0.89 MMP2 (0.47) CA2SLC7A5SMN1; SMN2CA1CASR
Valine SCHEMBL8035685 0.88 CA2 (0.46) CA2KIF11SLC7A5ALDH1A1SMN1; SMN2
Valine SCHEMBL8045567 0.88 CA2 (0.46) CA2KIF11SLC7A5ALDH1A1SMN1; SMN2
Valine SCHEMBL8045384 0.88 CA2 (0.46) CA2KIF11SLC7A5ALDH1A1SMN1; SMN2
SCHEMBL330904 0.81 CA2 (0.64) CA2ALDH1A1LMNASMN1; SMN2CA1
Valine SCHEMBL5159688 0.80 SLC1A3 (0.55) CA2KIF11SLC7A5ALDH1A1LMNA
Valine SCHEMBL2295611 0.80 SLC1A3 (0.55) CA2KIF11SLC7A5ALDH1A1LMNA
SCHEMBL7375171 0.79 CA2 (0.51) CA2KIF11ALDH1A1LMNASMN1; SMN2
SCHEMBL8430251 0.79 CA2 (0.62) CA2ALDH1A1LMNASMN1; SMN2CA1
Hydrochloric Acid SCHEMBL27609749 0.79 CA2 (0.62) CA2ALDH1A1LMNASMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748791-B1 Valine p-isopropylbenzene sulfonate and a process for purifying valine AJINOMOTO KK (JP) 1999-11-17 EP disclosed
US-5689001-A Process for purifying valine AJINOMOTO CO., INC. (JP) 1997-11-18 US disclosed
EP-0748791-A2 Valine p-isopropylbenzene sulfonate and a process for purifying valine Ajinomoto Co., Inc. (JP) 1996-12-18 EP disclosed