Valine

Valine

SCHEMBL8045567

CC(C)C(N)C(=O)O.CCc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.46
SLC7A5 Q01650 1/20 0.46
ALDH1A1 P00352 4/20 0.42
KIF11 P52732 1/20 0.41
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CASR P41180 1/20 0.40
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
GAA P10253 2/20 0.38
AKR1C3 P42330 2/20 0.38
ADAMTS4 O75173 1/20 0.38
TAS2R14 Q9NYV8 1/20 0.38
TSHR P16473 1/20 0.38
NT5E P21589 1/20 0.38
MAPT P10636 1/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
AKR1C2 P52895 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL8035685 1.00 CA2 (0.46) CA2SLC7A5ALDH1A1KIF11ATM
Valine SCHEMBL8045384 1.00 CA2 (0.46) CA2SLC7A5ALDH1A1KIF11ATM
Isoleucine SCHEMBL8047310 0.88 CA2 (0.44) CA2ALDH1A1KIF11ATML3MBTL1
Valine SCHEMBL8429982 0.88 CA2 (0.49) CA2SLC7A5ALDH1A1KIF11CASR
Isoleucine SCHEMBL8048122 0.88 CA2 (0.44) CA2ALDH1A1KIF11ATML3MBTL1
Isoleucine SCHEMBL8036378 0.88 CA2 (0.44) CA2ALDH1A1KIF11ATML3MBTL1
Isoleucine SCHEMBL8036374 0.88 CA2 (0.44) CA2ALDH1A1KIF11ATML3MBTL1
Isoleucine SCHEMBL8047805 0.88 CA2 (0.44) CA2ALDH1A1KIF11ATML3MBTL1
Valine SCHEMBL21352576 0.85 MMP2 (0.47) CA2SLC7A5CASRSLC1A3SLC1A2
SCHEMBL6355799 0.84 CA2 (0.45) CA2ALDH1A1KIF11ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6072083-A Method for purifying branched chain amino acids AJINOMOTO CO., INC. (JP) 2000-06-06 US claimed
US-6072083-A Method for purifying branched chain amino acids AJINOMOTO CO., INC. (JP) 2000-06-06 US disclosed