Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596339 | 0.84 | PNMT (0.58) | ALDH1A1SLC7A5IDO1LTA4H | |
| SCHEMBL8703262 | 0.84 | PNMT (0.58) | ALDH1A1SLC7A5IDO1LTA4H | |
| SCHEMBL32677002 | 0.84 | PNMT (0.58) | ALDH1A1SLC7A5IDO1LTA4H | |
| SCHEMBL5222169 | 0.84 | PNMT (0.58) | ALDH1A1SLC7A5IDO1LTA4H | |
| Hydrochloric Acid SCHEMBL27464747 | 0.83 | PNMT (0.57) | ALDH1A1SLC7A5IDO1LTA4H | |
| SCHEMBL28741488 | 0.83 | ALDH1A1 (0.42) | ALDH1A1SLC7A5CASRPTGS2 | |
| Hydrochloric Acid SCHEMBL27478281 | 0.83 | PNMT (0.57) | ALDH1A1SLC7A5IDO1LTA4H | |
| Hydrochloric Acid SCHEMBL27476980 | 0.83 | PNMT (0.57) | ALDH1A1SLC7A5IDO1LTA4H | |
| SCHEMBL1473553 | 0.83 | SLC6A2 (0.52) | ALDH1A1PTGS2 | |
| SCHEMBL2734777 | 0.83 | SLC6A2 (0.52) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | ALDH1A1 1305/4885SLC7A5 3222/4885CASR 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.