SCHEMBL8430355

SCHEMBL8430355

O=C1N[C@@H](c2cscn2)[C@H]1O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066558 0.66 PKM (0.38)
SCHEMBL8430376 0.64 HDAC8 (0.33)
Hydrochloric Acid SCHEMBL3646919 0.59 HRH4 (0.40)
SCHEMBL13811563 0.59 SMN1; SMN2 (0.45) KDM4E
SCHEMBL2112084 0.59 SMN1; SMN2 (0.45) KDM4E
SCHEMBL5521516 0.59 SMN1; SMN2 (0.45) KDM4E
SCHEMBL2112085 0.59 SMN1; SMN2 (0.45) KDM4E
SCHEMBL2112086 0.59 SMN1; SMN2 (0.45) KDM4E
SCHEMBL3075586 0.58 ALDH1A1 (0.51) KDM4E
SCHEMBL13580146 0.58 ALDH1A1 (0.51) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939561-A Process for the preparation of β-phenylisoserine and β-lactam and their analogues RHONE-POULENCE RORER S.A. (FR) 1999-08-17 US disclosed