SCHEMBL8430541

SCHEMBL8430541

O=C(O)C(=COCCCCc1ccc(F)cc1)c1cccc(CSc2c(F)cccc2F)n1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 19/20 0.42
PTGER1 P34995 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434140 0.94 LTB4R (0.47) LTB4RPTGER1
SCHEMBL8434513 0.91 LTB4R (0.53) LTB4RPTGER1
SCHEMBL8432889 0.86 LTB4R (0.57) LTB4RPTGER1
SCHEMBL8434525 0.85 LTB4R (0.50) LTB4R
SCHEMBL8430702 0.84 LTB4R (0.51) LTB4RPTGER1
SCHEMBL8430532 0.83 LTB4R (0.53) LTB4R
SCHEMBL8430422 0.83 LTB4R (0.51) LTB4R
SCHEMBL8434056 0.82 LTB4R (0.51) LTB4RPTGER1
SCHEMBL8434511 0.81 LTB4R (0.49) LTB4R
SCHEMBL8430615 0.80 LTB4R (0.60) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5929096-A TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS SMITHKLINE BEECHAM CORPORATION (US) 1999-07-27 US disclosed