Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 4/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472384 | 0.99 | MAPK1 (0.62) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11462219 | 0.96 | MAPK1 (0.62) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10346511 | 0.91 | SMN1; SMN2 (0.60) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11400162 | 0.85 | MEN1 (0.69) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10394932 | 0.85 | MEN1 (0.69) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11460096 | 0.85 | MEN1 (0.65) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10860941 | 0.84 | MAPK1 (0.64) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10856071 | 0.84 | MAPK1 (0.64) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL25286006 | 0.84 | ALDH1A1 (0.71) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL9010501 | 0.84 | ADORA2B (0.62) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1995026722-A1 | METHOD FOR INHIBITING MAST CELL AND BASOPHIL ACTIVATION | CELL THERAPEUTICS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |