Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842843 | 0.81 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL844394 | 0.80 | GPR35 (0.37) | KMT2AMEN1CHRNA7HTR3AHTR3E | |
| SCHEMBL843604 | 0.80 | CHRNA7 (0.36) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL843803 | 0.80 | CHRNA7 (0.39) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL843812 | 0.79 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL842775 | 0.78 | CHRNA7 (0.36) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL843377 | 0.77 | CHRNA7 (0.36) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL844330 | 0.77 | CHRNA7 (0.35) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL842569 | 0.77 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL844814 | 0.77 | CHRNA7 (0.37) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | claimed |