Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843113 | 0.80 | SLC26A4 (0.35) | MCL1MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL844330 | 0.79 | CHRNA7 (0.35) | ALDH1A1HPGDHTR3EHTR3BCHRNA7 | |
| SCHEMBL843803 | 0.78 | CHRNA7 (0.39) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL842843 | 0.77 | CHRNA7 (0.37) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL843928 | 0.76 | CHRNA7 (0.36) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL843604 | 0.76 | CHRNA7 (0.36) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL842935 | 0.76 | CHRNA7 (0.34) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL843834 | 0.76 | CHRNA7 (0.34) | KDM4EALDH1A1HPGDGAAHTR3E | |
| SCHEMBL843782 | 0.76 | CHRNA7 (0.35) | HTR3EHTR3BCHRNA7HTR3AHTR3D | |
| SCHEMBL843157 | 0.76 | CHRNA7 (0.35) | HTR3EHTR3BCHRNA7HTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | claimed |