SCHEMBL84314

SCHEMBL84314

CCc1ccc(Oc2cccc(Oc3ccc(N4C(=O)c5ccc(Oc6ccc(C(C)(C)c7ccc(Oc8ccc9c(c8)C(=O)N(CC)C9=O)cc7)cc6)cc5C4=O)cc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.53
ALDH1A1 P00352 4/20 0.44
PKM P14618 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
POLB P06746 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 2/20 0.41
NR1H3 Q13133 2/20 0.40
NR1H2 P55055 1/20 0.40
PTGES O14684 1/20 0.39
MAPK1 P28482 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR3 Q9UBY5 1/20 0.39
MCHR1 Q99705 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14438541 0.91 BRD4 (0.54) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL18650457 0.89 CA1 (0.43) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL22946547 0.87 ALDH1A1 (0.48) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL10000451 0.84 BRD4 (0.63) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL25550005 0.82 BRD4 (0.79) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL10000519 0.81 BRD4 (0.58) BRD4ALDH1A1NPSR1MEN1KMT2A
SCHEMBL22627170 0.81 PKM (0.53) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL84816 0.80 BRD4 (0.58) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL14438539 0.80 MEN1 (0.60) BRD4ALDH1A1PKMNPSR1MEN1
SCHEMBL84311 0.79 ALDH1A1 (0.49) ALDH1A1PKMNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8792318-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-29 US disclosed
US-20120155242-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-21 US disclosed
US-8129496-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-06 US disclosed