Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631333 | 0.84 | — | — | |
| SCHEMBL8896932 | 0.82 | FFAR1 (0.40) | FFAR1MAPTPPARDRECQLKMT2A | |
| SCHEMBL8896939 | 0.82 | FFAR1 (0.40) | FFAR1MAPTPPARDRECQLKMT2A | |
| SCHEMBL9033731 | 0.80 | ACE2 (0.41) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL657947 | 0.79 | ALOX5 (0.44) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL13740280 | 0.79 | GPR84 (0.33) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL657946 | 0.79 | ALOX5 (0.44) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL13740281 | 0.79 | GPR84 (0.33) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL9457346 | 0.78 | GPR84 (0.42) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL9842167 | 0.75 | GPR84 (0.44) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742223-B1 | A method of preparing a derivative of optically active azetidin-2-one | TAKASAGO PERFUMERY CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5712388-A | Method of preparing a derivative of optically active azetidin-2-one | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0742223-A1 | A method of preparing a derivative of optically active azetidin-2-one | Takasago International Corporation (JP) | 1996-11-13 | — | — | EP | disclosed |