Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431744 | 0.88 | ALOX15 (0.40) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL8733821 | 0.88 | TAAR1 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL8433433 | 0.88 | ADRB2 (0.41) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL8618970 | 0.88 | TAAR1 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8734036 | 0.87 | TAAR1 (0.45) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8620264 | 0.87 | TAAR1 (0.45) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL7940556 | 0.86 | ADRB2 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL7937815 | 0.86 | ADRB2 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL7937813 | 0.86 | ADRB2 (0.46) | ADRB2ADRB3ADRB1ADRA2AADRA2B | |
| SCHEMBL7233580 | 0.83 | CYP4F2 (0.45) | ADRB2ADRB3ADRB1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902900-A | OPTICAL PURITY, USE AS ANTI-OBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5679557-A | Process of asymmetrically reducing 1-phenyl-2-oxo-propane derivatives with microorganisms | DAICEL CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-10-21 | — | — | US | disclosed |