Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 18/20 | 0.58 |
| ▸ | MMP1 | P03956 | 18/20 | 0.58 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433179 | 0.91 | ADAM17 (0.68) | ADAM17MMP1MMP13 | |
| SCHEMBL7214512 | 0.82 | MMP1 (0.83) | ADAM17MMP1MMP13MMP3 | |
| SCHEMBL7220235 | 0.82 | MMP1 (0.83) | ADAM17MMP1MMP13MMP3 | |
| SCHEMBL5756924 | 0.81 | ADAM17 (0.82) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL8431603 | 0.79 | ADAM17 (0.56) | ADAM17MMP1MMP13 | |
| SCHEMBL5759603 | 0.79 | MMP1 (0.54) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL7507399 | 0.79 | MMP1 (0.54) | ADAM17MMP1MMP13MMP3MMP7 | |
| SCHEMBL8431700 | 0.77 | ADAM17 (0.56) | ADAM17MMP1MMP13 | |
| SCHEMBL8435856 | 0.77 | ADAM17 (0.58) | ADAM17MMP1MMP13 | |
| SCHEMBL7214373 | 0.77 | MMP1 (0.55) | ADAM17MMP1MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |