Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494584 | 0.91 | HDAC1 (0.55) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL648254 | 0.91 | HDAC1 (0.55) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL11699448 | 0.90 | TGM2 (0.70) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL1733998 | 0.90 | TGM2 (0.70) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1930429 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL28627653 | 0.90 | HDAC1 (0.54) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL23723888 | 0.89 | HDAC1 (0.56) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL9086439 | 0.89 | ITGB3 (0.60) | HDAC1HDAC2ITGB3ITGA2BCTSL | |
| SCHEMBL5692870 | 0.89 | ITGB3 (0.60) | HDAC1HDAC2ITGB3ITGA2BCTSL | |
| SCHEMBL8435352 | 0.88 | HDAC1 (0.63) | HDAC1HDAC2TGM2CTSLSSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885816-A | OPTICALLY RESOLVING A RACEMIC MIXTURE OF AMINO ACID DERIVATIVES, COMPRISING USING A NONSPECIFIC CATALYTIC ANTIBODY WHICH ENANTIOSELECTIVELY HYDROLIZES VARIOUS AMINO ACID ESTER DERIVATIVES | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0765940-A1 | CATALYTIC ANTIBODY WHICH HYDROLYZES AMINO ACID ESTER DERIVATIVE ENANTIOSELECTIVELY | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1997-04-02 | — | — | EP | disclosed |