Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16494584 | 1.00 | HDAC1 (0.55) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL1930429 | 0.99 | HDAC1 (0.54) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL28627653 | 0.99 | HDAC1 (0.54) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL23723888 | 0.98 | HDAC1 (0.56) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL8433172 | 0.91 | HDAC1 (0.65) | HDAC1HDAC2TGM2ITGB3ITGA2B | |
| SCHEMBL12091750 | 0.89 | TGM2 (0.57) | HDAC1HDAC2TGM2CTSLSIRT2 | |
| SCHEMBL2028970 | 0.89 | TGM2 (0.62) | HDAC1HDAC2TGM2DPP8SIRT2 | |
| SCHEMBL17737201 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL12874110 | 0.88 | TGM2 (0.56) | HDAC1HDAC2TGM2CTSLSIRT2 | |
| SCHEMBL11867075 | 0.87 | CTSL (0.49) | HDAC1HDAC2TGM2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323125-A | Composition suitable for enhancing the flexural properties of objects containing vegetable fibers | 科思创(荷兰)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4054334-A1 | COMPOSITIONS, USES AND METHODS FOR PREVENTION AND TREATMENT OF VIRAL PLANT INFECTIONS | HW Innovations B.V. (NL) | 2022-09-14 | — | — | EP | disclosed |
| EP-2397488-B1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | FEDERAL STATE BUDGETARY INSTITUTION RES ZAKUSOV INSTITUTE OF PHARMACOLOGY (RU) | 2019-03-27 | — | — | EP | disclosed |
| US-9683014-B2 | Dipeptide mimetics of NGF and BDNF neurotrophins | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2017-06-20 | — | — | US | disclosed |
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII (RU) | 2015-04-23 | — | — | US | disclosed |
| US-8617549-B2 | Bispecific nanobodies as a therapeutic for alzheimer's disease | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120230999-A1 | BISPECIFIC NANOBODIES AS A THERAPEUTIC FOR ALZHEIMER'S DISEASE | Arizona Board of Regents, a body Corporate of the State of Arizona, Acting for and on Behalf of Ariz (US) | 2012-09-13 | — | — | US | disclosed |
| EP-1824775-B1 | DEBRIDING COMPOSITION FROM BROMELAIN AND METHODS OF PRODUCTION THEREOF | MEDIWOUND LTD (IL) | 2012-06-13 | — | — | EP | disclosed |
| US-8119124-B2 | Debriding composition from bromelain and methods of production thereof | MEDIWOUND LTD. (IL) | 2012-02-21 | — | — | US | disclosed |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | UCHREZHDENIE ROSSIISKOI AKADEMII MEDITSYNSKIKH NAUK NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII IMENI V.V.ZAKUSOVA RAMN (RU) | 2011-12-22 | — | — | US | disclosed |
| WO-2001055205-A1 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001038486-A2 | KUNITZ-TYPE PROTEASE INHIBITOR POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-05-31 | — | — | WO | disclosed |
| US-5510531-A | ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS | SUNTORY LIMITED (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0624191-A1 | A METHOD TO MAINTAIN THE ACTIVITY IN POLYETHYLENE GLYCOL-MODIFIED PROTEOLYTIC ENZYMES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1994-11-17 | — | — | EP | disclosed |
| EP-0393457-B1 | Proteinase inhibitor | SUNTORY LTD (JP) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993015189-A1 | A METHOD TO MAINTAIN THE ACTIVITY IN POLYETHYLENE GLYCOL-MODIFIED PROTEOLYTIC ENZYMES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1993-08-05 | — | — | WO | disclosed |
| US-5081284-A | N-Oxomethyl-Substituted Peptide | SUNTORY LIMITED (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0393457-A1 | Proteinase inhibitor | SUNTORY LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4715899-A | Liquid cleaner containing inactivated protease for protein soiled contact lenses | CHANDA SUBIR (US) | 1987-12-29 | — | — | US | disclosed |
| US-3943245-A | CHROMATOGRAPHY | ARMOUR PHARMACEUTICAL COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111828-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | HDAC1 1701/4885HDAC2 1949/4885TGM2 3078/4885 |
| US-20120230999-A1 | BISPECIFIC NANOBODIES AS A THERAPEUTIC FOR ALZHEIMER'S DISEASE | BACE1, BACE2, PSEN1 | HDAC1 1327/4885HDAC2 1658/4885TGM2 901/4885 |
| US-20110312895-A1 | DIPEPTIDE MIMETICS OF NGF AND BDNF NEUROTROPHINS | BDNF, NTRK2, NGF | HDAC1 1701/4885HDAC2 1949/4885TGM2 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.