Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079894 | 0.82 | KMT2A (0.57) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL8434118 | 0.76 | CYP1A2 (0.48) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL18177840 | 0.73 | ALDH1A1 (0.76) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL15145811 | 0.71 | POLB (0.74) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL8290704 | 0.70 | ALDH1A1 (0.61) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL2795569 | 0.70 | GPR183 (0.63) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL1819229 | 0.70 | MAPT (0.58) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL11222973 | 0.69 | MAPT (0.61) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL7266077 | 0.69 | RECQL (0.65) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL2798066 | 0.68 | POLB (0.72) | KMT2APOLBMEN1GPR183GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5827887-A | 5-ALPHA REDUCTASE INHIBITORS | ROUSSEL UCLAF (FR) | 1998-10-27 | — | — | US | disclosed |