Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887136 | 0.94 | TSHR (0.54) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL14891456 | 0.92 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL14809987 | 0.92 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL28738660 | 0.92 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL759137 | 0.87 | TSHR (0.52) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL29224613 | 0.86 | DGAT1 (0.44) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL27834061 | 0.85 | TSHR (0.50) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL27659346 | 0.84 | TSHR (0.44) | TSHRLMNAALDH1A1RECQLPTPRB | |
| SCHEMBL3280394 | 0.83 | TSHR (0.39) | TSHRALDH1A1RECQLCYP4F2CYP4A11 | |
| SCHEMBL46134 | 0.83 | TSHR (0.48) | TSHRLMNAALDH1A1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146096-A | 2, 2-Dimethyl-5- (4-chlorobenzyl) cyclopentanone derivative and preparation method thereof | 浙江大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-111303053-B | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2023-01-17 | — | — | CN | disclosed |
| CN-110105556-A | Antibacterial aqueous printing ink composition including water-soluble sodium sulfonated polyester | 施乐公司 | 2019-08-09 | — | — | CN | disclosed |
| WO-2019110355-A1 | BRANCHED ADIPIC ACID BASED ESTERS AS NOVEL BASE STOCKS AND LUBRICANTS | BASF SE (DE) | 2019-06-13 | — | — | WO | disclosed |
| CN-105247124-B | Fiber structure | 东丽株式会社 | 2017-03-15 | — | — | CN | disclosed |
| CN-105247124-A | Fibrous structure | TORAY INDUSTRIES | 2016-01-13 | — | — | CN | disclosed |
| EP-0765857-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | MITSUBISHI RAYON CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5773240-A | Optically active α-substituted carboxylic acid derivatives and method for producing the same | MITSUBISHI RAYON CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0765857-A1 | OPTICALLY ACTIVE ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI RAYON CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |