Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162257 | 0.92 | ALDH1A1 (0.48) | TSHRALDH1A1LMNASLC22A6CYP4F2 | |
| SCHEMBL161711 | 0.87 | NAALAD2 (0.45) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL9429165 | 0.85 | NAALAD2 (0.44) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL8433296 | 0.83 | TSHR (0.56) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL3280394 | 0.83 | TSHR (0.39) | TSHRALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL4100780 | 0.80 | CYP4F2 (0.62) | TSHRALDH1A1SLC22A6CYP4F2CYP4A11 | |
| SCHEMBL28174201 | 0.80 | CYP4F2 (0.41) | TSHRALDH1A1CYP4F2CYP4A11TDP1 | |
| SCHEMBL2022397 | 0.79 | DGAT1 (0.44) | TSHRALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL3278280 | 0.79 | CYP4F2 (0.43) | TSHRALDH1A1CYP4F2CYP4A11TDP1 | |
| SCHEMBL29224613 | 0.79 | DGAT1 (0.44) | TSHRALDH1A1LMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440126-B1 | PROCESS FOR OBTAINING THIN FILMS AND FILM-FORMING ARTICLES | GAYLORD CHEMICAL COMPANY LLC (US) | 2024-06-05 | — | — | EP | disclosed |
| EP-3353237-B1 | SOLVENT SYSTEM COMPRISING A MIXTURE OF DIMETHYL SULFOXIDE AND AT LEAST ONE LACTONE | ARKEMA FRANCE (FR) | 2024-05-08 | — | — | EP | disclosed |
| EP-3440126-A1 | PROCESS FOR OBTAINING THIN FILMS AND FILM-FORMING ARTICLES | Arkema France (FR) | 2019-02-13 | — | — | EP | disclosed |
| EP-3002285-B1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2018-08-29 | — | — | EP | disclosed |
| EP-3353237-A1 | SOLVENT SYSTEM COMPRISING A MIXTURE OF DIMETHYL SULFOXIDE AND AT LEAST ONE LACTONE | Arkema France (FR) | 2018-08-01 | — | — | EP | disclosed |
| EP-3350161-A1 | USE OF COMPOUNDS INCLUDING A SULFOXIDE OR SULFONE FUNCTION AND AN AMIDE FUNCTION AS SOLVENTS AND NEW SOLVENTS | Arkema France (FR) | 2018-07-25 | — | — | EP | disclosed |
| EP-3350257-A1 | SOLVENT COMPOSITION COMPRISING A MIXTURE OF A MOLECULE HAVING A SULPHOXIDE FUNCTION AND A MOLECULE HAVING AN AMIDE FUNCTION | Arkema France (FR) | 2018-07-25 | — | — | EP | disclosed |
| US-9974777-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-9974777-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| US-9862721-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-20130345426-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-12-26 | — | — | US | disclosed |
| EP-2592081-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2013-05-15 | — | — | EP | disclosed |
| EP-2592081-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109699-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012127885-A1 | TETRAHYDROCARBOLINE DERIVATIVE | 小野薬品工業株式会社 (JP) | 2012-09-27 | — | — | WO | disclosed |
| WO-2012005227-A1 | TETRAHYDROCARBOLINE DERIVATIVE | 小野薬品工業株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |
| CN-1175321-C | Toner and image forming method | ������������ʽ���� | 2004-11-10 | — | — | CN | disclosed |
| CN-1151409-C | Toner for developing electrostatic image, apparatus unit and image forming method | 佳能株式会社 | 2004-05-26 | — | — | CN | disclosed |
| CN-1236908-A | Toner and image forming method | CANON KK (JP) | 1999-12-01 | — | — | CN | disclosed |
| CN-1164050-A | Toner for developing electrostatic image, apparatus unit and image forming method | CANON KK (JP) | 1997-11-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345426-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | TSHR 4617/4885ALDH1A1 1081/4885LMNA 3264/4885 |
| US-20130109699-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | TSHR 4617/4885ALDH1A1 1081/4885LMNA 3264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.