Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | RHEB | Q15382 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784489 | 0.86 | PDE7A (0.50) | MEN1KMT2AHTR1AHTR3ARHEB | |
| SCHEMBL28016927 | 0.83 | NR1H2 (0.52) | MEN1KMT2ASLC6A4CYP2D6CYP2C9 | |
| SCHEMBL9475092 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL30958573 | 0.82 | SLC6A4 (0.53) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL8432424 | 0.80 | FBP1 (0.44) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL6915666 | 0.80 | RHEB (0.55) | KMT2ARHEBALDH1A1LMNANPSR1 | |
| SCHEMBL29543966 | 0.80 | RHEB (0.55) | KMT2ARHEBALDH1A1LMNANPSR1 | |
| SCHEMBL1713296 | 0.78 | CYP1A2 (0.53) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL7524798 | 0.78 | MEN1 (0.53) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL31016398 | 0.78 | CYP1A2 (0.53) | MEN1KMT2ASLC6A4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998670-A | Method of making high purity substituted diphenyldisulfides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1991006533-A1 | NOVEL PROCESS FOR MANUFACTURING COMPOUNDS WITH VALUABLE PHARMACOLOGICAL PROPERTIES AND NEW INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-16 | — | — | WO | disclosed |