SCHEMBL1713296

SCHEMBL1713296

Nc1ccccc1Sc1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.53
CYP3A4 P08684 6/20 0.53
ALDH1A1 P00352 5/20 0.53
CYP2C9 P11712 5/20 0.53
CYP2C19 P33261 4/20 0.53
KDM4E B2RXH2 3/20 0.53
HPGD P15428 3/20 0.53
SLC6A4 P31645 1/20 0.50
PDE7A Q13946 2/20 0.49
DHFR P00374 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
MAPT P10636 4/20 0.48
NPSR1 Q6W5P4 3/20 0.48
APOBEC3G Q9HC16 1/20 0.48
PKM P14618 1/20 0.47
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP2D6 P10635 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31016398 1.00 CYP1A2 (0.53) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL3095695 0.83 CYP3A4 (0.56) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL11546 0.82 MAPT (0.56) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL29613097 0.82 MAPT (0.56) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL5211034 0.80 MAPT (0.54) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL2614720 0.79 DHFR (0.49) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL546833 0.79 DHFR (0.49) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL2850872 0.79 HPGD (0.58) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL30567099 0.79 DHFR (0.49) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19
SCHEMBL4962252 0.79 MEN1 (0.53) CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-20160274084-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC 2016-09-22 US disclosed
US-9341576-B2 Detection of vapor phase compounds by changes in physical properties of a liquid crystal PLATYPUS TECHNOLOGIES, LLC (US) 2016-05-17 US disclosed
US-20160018371-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2016-01-21 US disclosed
WO-2014165196-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC (US) 2014-10-09 WO disclosed
US-20120288951-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2012-11-15 US disclosed
US-8178355-B2 Detection of vapor phase compounds by changes in physical properties of a liquid crystal PLATYPUS TECHNOLOGIES, LLC. (US) 2012-05-15 US disclosed
EP-2344879-A2 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL Platypus Technologies, LLC (US) 2011-07-20 EP disclosed
US-20100093096-A1 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2010-04-15 US disclosed
WO-2010031047-A2 DETECTION OF VAPOR PHASE COMPOUNDS BY CHANGES IN PHYSICAL PROPERTIES OF A LIQUID CRYSTAL PLATYPUS TECHNOLOGIES, LLC (US) 2010-03-18 WO disclosed
US-6403607-B1 ANTIULCER Hidaka, Hiroyoshi (JP) 2002-06-11 US disclosed
EP-1072587-A1 SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT Hidaka, Hiroyoshi (JP) 2001-01-31 EP disclosed
EP-0102476-A1 Method of modulating the immune response system in mammals AMERICAN CYANAMID COMPANY (US) 1984-03-14 EP disclosed