Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433550 | 1.00 | CTSL (0.55) | CTSLMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL10794620 | 0.89 | HTR2A (0.56) | CTSLMEN1KMT2ANPC1TP53 | |
| SCHEMBL1801469 | 0.89 | HTR2A (0.56) | CTSLMEN1KMT2ANPC1TP53 | |
| SCHEMBL8432555 | 0.89 | CTSB (0.53) | CTSLMEN1KMT2ACTSB | |
| SCHEMBL8432553 | 0.89 | CTSB (0.53) | CTSLMEN1KMT2ACTSB | |
| SCHEMBL11797739 | 0.88 | CTSL (0.57) | CTSLMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL11797734 | 0.88 | CTSL (0.57) | CTSLMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL15080869 | 0.88 | CTSK (0.61) | CTSLMEN1KMT2ALMNACTSB | |
| SCHEMBL30946598 | 0.88 | CTSK (0.61) | CTSLMEN1KMT2ALMNACTSB | |
| SCHEMBL12193557 | 0.88 | MEN1 (0.68) | CTSLMEN1KMT2ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885816-A | OPTICALLY RESOLVING A RACEMIC MIXTURE OF AMINO ACID DERIVATIVES, COMPRISING USING A NONSPECIFIC CATALYTIC ANTIBODY WHICH ENANTIOSELECTIVELY HYDROLIZES VARIOUS AMINO ACID ESTER DERIVATIVES | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0765940-A1 | CATALYTIC ANTIBODY WHICH HYDROLYZES AMINO ACID ESTER DERIVATIVE ENANTIOSELECTIVELY | PROTEIN ENGINEERING RESEARCH INSTITUTE (JP) | 1997-04-02 | — | — | EP | disclosed |