SCHEMBL8433717

SCHEMBL8433717

CCCCCCC(CC(=O)O)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.56
MAPT P10636 1/20 0.48
FFAR1 O14842 2/20 0.46
FFAR4 Q5NUL3 1/20 0.46
FDPS P14324 1/20 0.44
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
MMP2 P08253 5/20 0.43
MMP3 P08254 5/20 0.43
MMP1 P03956 3/20 0.43
MMP7 P09237 1/20 0.43
S1PR2 O95136 1/20 0.43
S1PR1 P21453 1/20 0.43
HSPD1 P10809 1/20 0.42
BLM P54132 1/20 0.42
HSPE1 P61604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433897 0.92 GPR84 (0.46) GPR84MAPTFFAR1FFAR4FDPS
Hydrochloric Acid SCHEMBL9624578 0.91 GPR84 (0.44) GPR84MAPTFFAR1FFAR4FDPS
SCHEMBL18822157 0.85 GPR84 (0.52) GPR84MAPTFFAR1FFAR4FDPS
SCHEMBL499817 0.84 GPR84 (0.39) GPR84MAPTS1PR2S1PR1ALDH1A1
SCHEMBL10346410 0.84 FFAR4 (0.53) GPR84MAPTFFAR1FFAR4PPARD
SCHEMBL27739801 0.84 FFAR4 (0.53) GPR84MAPTFFAR1FFAR4PPARD
SCHEMBL28184366 0.83 GPR84 (0.58) GPR84MAPTFFAR1FFAR4FDPS
Bicarbonate SCHEMBL10346411 0.83 MAPT (0.50) GPR84MAPTFFAR1FFAR4FDPS
SCHEMBL11777994 0.83 GPR84 (0.50) GPR84MAPTFFAR1FFAR4FDPS
SCHEMBL28184417 0.81 GPR84 (0.55) GPR84MAPTFFAR1FFAR4FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499221-B1 Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1999-12-08 EP disclosed
EP-0440134-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1994-09-21 EP disclosed
EP-0300497-B1 Optically active compound, process for producing same and liquid crystal composition containing same CANON KK (JP) 1994-03-02 EP disclosed
US-5281362-A Ferroelectric liquid crystals for optics CANON KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed
US-5217644-A MESOMORPHIC COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME, LIQUID CRYSTAL DEVICE USING SAME AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-06-08 US disclosed
EP-0499221-A1 Optically active compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
US-5126071-A Optically active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1992-06-30 US disclosed
EP-0440134-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed
US-4917817-A Optical active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1990-04-17 US disclosed
EP-0300497-A1 Optically active compound, process for producing same and liquid crystal composition containing same CANON KABUSHIKI KAISHA (JP) 1989-01-25 EP disclosed