Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070481 | 0.83 | SLC6A4 (0.54) | SLC6A4PPARGPPARA | |
| SCHEMBL3294896 | 0.83 | SLC6A4 (0.54) | SLC6A4PPARGPPARA | |
| SCHEMBL13484519 | 0.75 | ALDH1A1 (0.50) | MAPTMEN1KMT2AALDH1A1ANPEP | |
| SCHEMBL11081034 | 0.75 | APAF1 (0.54) | MAPTMEN1KMT2AALDH1A1ANPEP | |
| SCHEMBL13484773 | 0.75 | KMT2A (0.53) | KDM4EMAPTHPGDMEN1KMT2A | |
| SCHEMBL27929812 | 0.75 | APAF1 (0.54) | MAPTMEN1KMT2AALDH1A1ANPEP | |
| SCHEMBL12450939 | 0.75 | APAF1 (0.54) | MAPTMEN1KMT2AALDH1A1ANPEP | |
| SCHEMBL3971356 | 0.75 | SLC6A4 (0.47) | SLC6A4KDM4EPPARGPPARAHAO1 | |
| SCHEMBL8433730 | 0.75 | SLC6A4 (0.50) | SLC6A4KDM4EMAPTPPARGPPARA | |
| SCHEMBL7394066 | 0.74 | SLC6A4 (0.52) | SLC6A4KDM4EPPARGPPARAHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |