Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369511 | 0.85 | GAA (0.55) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8432964 | 0.82 | KMT2A (0.47) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL1070481 | 0.76 | SLC6A4 (0.54) | SLC6A4PPARGPPARA | |
| SCHEMBL3294896 | 0.76 | SLC6A4 (0.54) | SLC6A4PPARGPPARA | |
| SCHEMBL8433732 | 0.75 | SLC6A4 (0.52) | SLC6A4KDM4EMAPTHPGDNPC1 | |
| SCHEMBL31713831 | 0.74 | SLC6A4 (0.54) | SLC6A4KDM4EMAPTHPGDNPC1 | |
| SCHEMBL8935431 | 0.73 | MEN1 (0.44) | SLC6A4KDM4EHPGDNPC1RAB9A | |
| SCHEMBL8935425 | 0.73 | MEN1 (0.44) | SLC6A4KDM4EHPGDNPC1RAB9A | |
| SCHEMBL10683546 | 0.71 | PTGS2 (0.54) | SLC6A4PPARGPPARAHAO1LMNA | |
| SCHEMBL8832825 | 0.71 | SLC6A4 (0.54) | SLC6A4KDM4EMAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | claimed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |