Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400815 | 0.79 | TACR3 (0.57) | ALDH1A1MAPTKMT2ATACR3TP53 | |
| SCHEMBL23682656 | 0.71 | TACR3 (0.83) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL9785880 | 0.69 | TACR3 (0.57) | ALDH1A1KMT2ATACR3TP53HSD17B10 | |
| SCHEMBL6485095 | 0.68 | ALDH1A1 (0.64) | GAAALDH1A1LMNAKMT2ATACR3 | |
| SCHEMBL7362106 | 0.68 | ALDH1A1 (0.64) | GAAALDH1A1LMNAKMT2ATACR3 | |
| SCHEMBL7370375 | 0.67 | KMT2A (0.54) | GAAHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18435561 | 0.67 | POLB (0.71) | GAAALDH1A1TDP1KMT2ATACR3 | |
| SCHEMBL27182285 | 0.67 | HTT (0.80) | HTTALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL8719887 | 0.66 | XDH (0.37) | GAAHTTALDH1A1LMNAKMT2A | |
| SCHEMBL2243090 | 0.66 | ALDH1A1 (0.64) | GAAALDH1A1LMNAKMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886191-A | ANTICOAGULANTS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-03-23 | — | — | US | disclosed |