SCHEMBL8433852

SCHEMBL8433852

C=Cc1ccc(CSc2ccccc2C(=O)O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRG P23470 1/20 0.58
CYP1A2 P05177 2/20 0.51
KMT2A Q03164 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
RAB9A P51151 4/20 0.48
PRNP P04156 1/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 3/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CYP2C9 P11712 2/20 0.44
NPC1 O15118 2/20 0.43
HSP90AA1 P07900 1/20 0.43
PTPRC P08575 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1901284 0.84 PTPRG (0.67) PTPRGCYP1A2KMT2AL3MBTL1RAB9A
SCHEMBL4021020 0.77 KDR (0.60) PTPRGCYP1A2KMT2AL3MBTL1RAB9A
SCHEMBL8749795 0.77 KMT2A (0.40) PTPRGKMT2AL3MBTL1MEN1POLB
SCHEMBL6290570 0.77 RAB9A (0.67) PTPRGCYP1A2KMT2AL3MBTL1RAB9A
SCHEMBL6231914 0.75 CYP1A2 (0.71) PTPRGCYP1A2KMT2ARAB9APRNP
SCHEMBL9716018 0.75 PTPRG (0.68) PTPRGCYP1A2KMT2AL3MBTL1RAB9A
SCHEMBL6248402 0.74 CYP1A2 (0.61) PTPRGCYP1A2RAB9APOLBGAA
Benzene SCHEMBL27474313 0.74 CYP1A2 (0.61) PTPRGCYP1A2RAB9APOLBGAA
SCHEMBL30363164 0.74 ALDH1A1 (0.39) CYP1A2POLBALDH1A1KDM4ECA1
SCHEMBL15143209 0.74 CYP1A2 (0.65) PTPRGCYP1A2KMT2ARAB9APRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP claimed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP claimed
US-5278267-A Water insoluble vinyl aromatic polymer EASTMAN KODAK COMPANY (US) 1994-01-11 US claimed
US-5210289-A Homo or coploymers for medical diagnosis EASTMAN KODAK COMPANY (US) 1993-05-11 US claimed
US-5155166-A Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers EASTMAN KODAK COMPANY (US) 1992-10-13 US claimed
US-5149737-A Carboxy group extended from polymer surface allows easier attachment of biological substances EASTMAN KODAK COMPANY (US) 1992-09-22 US claimed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US claimed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP claimed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP claimed
US-5888723-A SENSITIVE HYBRIDIZATION ASSAY USING NUCLEIC ACID REAGENT COMPOSED OF OLIGONUCLEOTIDES COVALENTLY ATTACHED TO POLYMER PARTICLES WHICH ARE ADHERED TO SUPPORT USING WATER INSOLUBLE ADHESIVE; LOW BACKGROUND JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1999-03-30 US disclosed
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP disclosed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP disclosed
EP-0530357-B1 ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES JOHNSON & JOHNSON CLIN DIAG (US) 1995-11-15 EP disclosed
US-5147777-A Analysis, diagnosis EASTMAN KODAK COMPANY (US) 1992-09-15 US disclosed
EP-0468585-A2 Biologically active reagent, analytical element and methods for use of the reagent Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-29 EP disclosed
EP-0466220-A2 Carboxy containing monomers and polymers and latices prepared from same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1992-01-15 EP disclosed
EP-0462670-A1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed
EP-0462644-A1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1991-12-27 EP disclosed