Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918303 | 0.87 | MEN1 (0.37) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8432245 | 0.75 | MEN1 (0.35) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8542481 | 0.70 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL8434063 | 0.67 | POLB (0.36) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8385965 | 0.67 | MEN1 (0.44) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL7509156 | 0.67 | RPS6KA3 (0.35) | ALDH1A1LMNA | |
| SCHEMBL7510124 | 0.66 | L3MBTL1 (0.40) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7651003 | 0.66 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPT | |
| SCHEMBL8436633 | 0.66 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPT | |
| SCHEMBL7510824 | 0.65 | MAPT (0.31) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869686-A | Substituted pyrazole derivatives, processes for their preparation and their use as herbicides | HOECHST SCHERING AGREVO GMBH (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5756424-A | POTENTIATION | HOECHST SCHERING AGREVO GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5580986-A | HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-12-03 | — | — | US | disclosed |
| CN-1087342-A | Novel substituted pyrazole derivatives, process for their preparation and their use as herbicides | SCHERING AG (DE) | 1994-06-01 | — | — | CN | disclosed |