Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431463 | 0.89 | CNR2 (0.39) | L3MBTL1CNR2HDAC1HDAC2 | |
| SCHEMBL8431552 | 0.88 | L3MBTL1 (0.42) | L3MBTL1MCHR1SSTR3SSTR5SSTR2 | |
| SCHEMBL10417607 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL6797796 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL10824776 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL6807464 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL6807462 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL6797801 | 0.80 | L3MBTL1 (0.40) | L3MBTL1MCHR1 | |
| SCHEMBL8435107 | 0.80 | TLR4 (0.36) | CNR2CNR1HDAC1HDAC2 | |
| SCHEMBL8435577 | 0.80 | L3MBTL1 (0.39) | L3MBTL1CNR2CNR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |