Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511501 | 0.93 | L3MBTL1 (0.40) | L3MBTL1CNR2SMPD1BCHEBRD4 | |
| SCHEMBL8431463 | 0.89 | CNR2 (0.39) | L3MBTL1CNR2SMPD1BRD4 | |
| SCHEMBL10418920 | 0.82 | TLR4 (0.41) | L3MBTL1CNR2BCHECNR1SELP | |
| SCHEMBL8434876 | 0.81 | TLR4 (0.43) | SMPD1SELP | |
| SCHEMBL8434878 | 0.81 | TLR4 (0.43) | SMPD1SELP | |
| SCHEMBL6800462 | 0.80 | TLR4 (0.46) | L3MBTL1BCHESELP | |
| SCHEMBL6800467 | 0.80 | TLR4 (0.46) | L3MBTL1BCHESELP | |
| SCHEMBL8435107 | 0.80 | TLR4 (0.36) | CNR2CNR1 | |
| SCHEMBL8436204 | 0.80 | TLR4 (0.42) | L3MBTL1BCHESELP | |
| SCHEMBL8436202 | 0.80 | TLR4 (0.42) | L3MBTL1BCHESELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |