Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 10/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435577 | 0.80 | L3MBTL1 (0.39) | CNR2CNR1 | |
| SCHEMBL8434091 | 0.80 | L3MBTL1 (0.37) | HDAC1HDAC2CNR2CNR1 | |
| SCHEMBL9511906 | 0.76 | TLR4 (0.41) | TLR4LY96HDAC1HDAC2 | |
| SCHEMBL8433658 | 0.76 | SMPD1 (0.44) | HDAC1HDAC2CNR2 | |
| SCHEMBL9512979 | 0.74 | TLR4 (0.38) | TLR4LY96HDAC1HDAC2 | |
| SCHEMBL8436423 | 0.74 | S1PR2 (0.31) | — | |
| SCHEMBL8436422 | 0.74 | S1PR2 (0.31) | — | |
| SCHEMBL6801798 | 0.73 | TLR4 (0.41) | TLR4LY96 | |
| SCHEMBL8432789 | 0.73 | SSTR3 (0.45) | HDAC1 | |
| SCHEMBL9511501 | 0.73 | L3MBTL1 (0.40) | HDAC1HDAC2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |