Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434213 | 0.77 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL6972578 | 0.76 | — | — | |
| SCHEMBL20178600 | 0.73 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9139865 | 0.70 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL850225 | 0.69 | PPARA (0.56) | AGTR1AGTR2 | |
| SCHEMBL7268388 | 0.69 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL5547472 | 0.69 | AGTR1 (0.72) | AGTR1 | |
| SCHEMBL11843092 | 0.67 | ALOX5 (0.43) | — | |
| SCHEMBL9516446 | 0.66 | CA12 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9386724 | 0.66 | AGTR1 (0.65) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | disclosed |