Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061315 | 0.81 | — | — | |
| SCHEMBL1469412 | 0.80 | CA1 (0.35) | TSHR | |
| SCHEMBL654463 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL11261469 | 0.75 | TSHR (0.33) | TSHR | |
| SCHEMBL1128339 | 0.74 | HDAC7 (0.37) | TSHR | |
| SCHEMBL11171620 | 0.73 | — | — | |
| SCHEMBL252600 | 0.73 | — | — | |
| Methylene Chloride SCHEMBL25381848 | 0.70 | — | — | |
| SCHEMBL9048220 | 0.70 | PRKCA (0.34) | — | |
| SCHEMBL8990510 | 0.70 | CTSK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936083-A | BACTERICIDES | Uclaf, Roussel (FR) | 1999-08-10 | — | — | US | disclosed |
| US-5541318-A | Cephalosporins | ROUSSEL UCLAF (FR) | 1996-07-30 | — | — | US | disclosed |
| US-5416080-A | Cephalosporins | ROUSSEL-UCLAF (FR) | 1995-05-16 | — | — | US | disclosed |
| US-5397779-A | Cephalosporins | ROUSSEL-UCLAF (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5373001-A | Antibiotics | ROUSSEL UCLAF (FR) | 1994-12-13 | — | — | US | disclosed |