Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28868727 | 0.98 | MAPT (0.42) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| Methane SCHEMBL27690559 | 0.81 | SLC18A3 (0.43) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6494087 | 0.80 | MAPT (0.47) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL21163358 | 0.79 | FFAR1 (0.48) | MAPTALDH1A1KDM4EL3MBTL1HTT | |
| SCHEMBL20004455 | 0.79 | HPGD (0.42) | ALDH1A1KDM4EGAAL3MBTL1KMT2A | |
| SCHEMBL8502504 | 0.79 | L3MBTL1 (0.44) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL27812326 | 0.76 | L3MBTL3 (0.33) | L3MBTL1FFAR1L3MBTL3 | |
| SCHEMBL6607096 | 0.76 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL22334722 | 0.75 | TRIM24 (0.50) | ALDH1A1KDM4ESMN1; SMN2FFAR1 | |
| SCHEMBL78460 | 0.75 | FFAR1 (0.43) | MAPTALDH1A1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962452-A1 | Oxidative hair dye compositions and methods containing 1-(4-aminophenyl)-2-pyrrolidinemethanols | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-08 | — | — | EP | claimed |
| US-5993491-A | Oxidative hair dye compositions and methods containing 1-(4-aminophenyl)-2-pyrrolidinemethanols | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-11-30 | — | — | US | claimed |