Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.61 |
| ▸ | CDC25B | P30305 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600128 | 0.80 | CDC25A (0.52) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL30002742 | 0.76 | CDC25B (1.00) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL3414838 | 0.76 | CDC25B (1.00) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL9627431 | 0.74 | CDC25A (0.65) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL9655485 | 0.74 | CDC25A (0.64) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL12592463 | 0.69 | CDC25A (0.58) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL5590298 | 0.69 | CDC25A (0.56) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL9629285 | 0.68 | MAOA (0.70) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| Mimosamycin SCHEMBL29884075 | 0.67 | CDC25A (0.46) | CDC25ACDC25BMAPTALDH1A1KDM4E | |
| SCHEMBL14398053 | 0.67 | CDC25B (0.83) | CDC25ACDC25BMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889185-A | Method of synthesizing isoindolequinones and derivatives thereof | THE UNIVERSITY OF AKRON (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998046567-A1 | METHOD OF SYNTHESIZING ISOINDOLEQUINONES AND DERIVATIVES THEREOF | THE UNIVERSITY OF AKRON (US) | 1998-10-22 | — | — | WO | disclosed |