Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615437 | 0.84 | RAB9A (0.57) | MAOBBCHEMAOALMNASMN1; SMN2 | |
| SCHEMBL4430103 | 0.83 | BACE1 (0.52) | BACE1NR1H2MAOBMRGPRX4CYP4F2 | |
| SCHEMBL10965286 | 0.79 | KDM4E (0.51) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL379281 | 0.78 | MAOB (0.67) | MAOBMRGPRX4CYP4F2CYP4A11BCHE | |
| SCHEMBL2137838 | 0.77 | MRGPRX4 (0.69) | MAOBMRGPRX4CYP4F2CYP4A11BCHE | |
| SCHEMBL11681206 | 0.76 | NR1H2 (0.49) | BACE1NR1H2MAOBCHRNB2CHRNB4 | |
| SCHEMBL30310041 | 0.76 | MAOB (0.50) | MAOBSMN1; SMN2 | |
| SCHEMBL28994891 | 0.76 | MAOB (0.50) | MAOBSMN1; SMN2 | |
| SCHEMBL6166011 | 0.76 | MAOB (0.49) | BACE1NR1H2MAOBCHRNB2CHRNB4 | |
| SCHEMBL16432914 | 0.76 | MAOB (0.49) | BACE1MAOBMRGPRX4CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |