Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684606 | 0.82 | LTA4H (0.50) | MEN1KMT2ATSHR | |
| SCHEMBL8439547 | 0.76 | TEAD4 (0.47) | TEAD4ALDH1A1TDP1MAPTPOLB | |
| SCHEMBL193222 | 0.75 | — | — | |
| SCHEMBL95343 | 0.75 | TEAD4 (0.74) | TEAD4ALDH1A1TDP1MAPTPOLB | |
| SCHEMBL83814 | 0.75 | TEAD4 (0.74) | TEAD4ALDH1A1TDP1MAPTPOLB | |
| SCHEMBL83863 | 0.75 | TEAD4 (0.74) | TEAD4ALDH1A1TDP1MAPTPOLB | |
| SCHEMBL884180 | 0.74 | — | — | |
| SCHEMBL491210 | 0.73 | ALDH1A1 (0.68) | TEAD4ALDH1A1TDP1MAPTPOLB | |
| SCHEMBL15063844 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| Phosphine SCHEMBL22361928 | 0.72 | TEAD4 (0.70) | TEAD4ALDH1A1TDP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |