Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | SCN4A | P35499 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722790 | 0.87 | CYP3A4 (0.59) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL31114638 | 0.87 | CYP3A4 (0.59) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL9474730 | 0.83 | RAB9A (0.59) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL16276940 | 0.81 | RAB9A (0.56) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL8433950 | 0.81 | RAB9A (0.56) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL5683354 | 0.81 | CYP3A4 (0.49) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL17610032 | 0.81 | RAB9A (0.56) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2552313 | 0.78 | CYP3A4 (0.53) | CYP3A4RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL2678487 | 0.78 | ILK (0.56) | CYP3A4RAB9ASMN1; SMN2TP53CYP1A2 | |
| SCHEMBL29741739 | 0.78 | ILK (0.56) | CYP3A4RAB9ASMN1; SMN2TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788491-B1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1999-12-01 | — | — | EP | disclosed |
| US-5795903-A | 6-polyfluoroalkoxy-and 6-polyfluoroalkyl-2-aminobenzothiazole derivatives | RHONE-POULENC RORER S.A. (FR) | 1998-08-18 | — | — | US | disclosed |
| EP-0788491-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | Aventis Pharma S.A. (FR) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996013492-A1 | 6-POLYFLUOROALKOXY AND 6-POLYFLUOROALKYL-2-AMINOBENZOTHIAZOLE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-05-09 | — | — | WO | disclosed |